Showing 1 to 10 of 91 Search Results:
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Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: May 25, 2022
Volume/Page: 239:113682.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Hippocampus, Animal offspring, Developmental neurotoxicant, Neurotoxicity, Pregnant animal
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Evaluation of Metformin and Dehydrozingerone against fluorosis induced neurodevelopmental toxicity in preclinical models.
Ahuja T, Kumar N, Begum F, Shenoy RR.
Journal Name: Alzheimers Dementia
Publish Date: December 31, 2021
Volume/Page: Suppl 12:e058668.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Lipid peroxidation, Protective effect
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Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Zhang Y, Han X, Tang Y, Zhang J, Hu Z, Xu W, Yao P, Niu Q.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: December 22, 2021
Volume/Page: [Epub ahead of print]. 230:113108 (2022).
Type: Animal Study
Categories: Brain, Cognitive Function, Mechanisms of Cellular Toxicity, Apoptosis, Autophagy, Neurotoxicity
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Fluoride alters feeding and memory in Lymnaea stagnalis.
Wiley B, Batabyal A, Lukowiak K.
Journal Name: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
Publish Date: December 2, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Cognitive Function, Canada
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Sirt3-mediated mitochondrial dysfunction is involved in fluoride-induced cognitive deficits.
Wang D, Cao L, Pan S, Wang G, Wang L, Cao N, Hao X.
Journal Name: Food and Chemical Toxicology
Publish Date: November 12, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Neurotoxicity, Sirt3
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Pharmacological implications of ipriflavone against environmental metal-induced neurodegeneration and dementia in rats.
Hussien HM, Ghareeb DA, Ahmed HEA, Hafez HS, Saleh SR.
Journal Name: Environmental Science and Pollution Research
Publish Date: July 7, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Susceptible Populations, Genetics, Amyloid plaques, Dementia, Protective effect
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Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice.
Xin J, Wang H, Sun N, Bughio S, Zeng D, Li L, Wang Y, Khalique A, Zeng Y, Pan K, Jing B, Ma H, Bai Y, Ni X.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: March 30, 2021
Volume/Page: 215:112108.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Gastrointestinal, Hippocampus, Protective effect
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Integrated transcriptomic and proteomic analysis indicated that neurotoxicity of rats with chronic fluorosis may be in mechanism involved in the changed cholinergic pathway and oxidative stress.
Ran LY, Xiang J, Zeng, XX, Tang JL, Dong YT, Zhang F, Yu WF, Qi XL, Xiao Y, Zou J, Deng J, Guan ZZ.
Journal Name: Journal of Trace Elements in Medicine and Biology
Publish Date: November 20, 2020
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Neurotoxicity
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Gut microbiota perturbations and neurodevelopmental impacts in offspring rats concurrently exposure to inorganic arsenic and fluoride.
Qiu Y, Chen X, Yan X, Wang J, Yu G, Ma W, Xiao B, Quinones S, Tian X, Ren X.
Journal Name: Environment International
Publish Date: July 2020
Volume/Page: 140:105763.
Type: Animal Study
Categories: Brain, Behavior, Brain Cellular/Tissue Effects, Cognitive Function, Gastrointestinal, Susceptible Populations, Chemical Co-Exposures, Arsenic, Hippocampus, Animal offspring, Developmental neurotoxicant, Neurotoxicity
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SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.
Zhao Q, Tian Z, Zhou G, Niu Q, Chen J, Li P, Dong L, Xia T, Zhang S, Wang A.
Journal Name: Theranostics
Publish Date: March 26, 2020
Volume/Page: 10(11):4822-4838.
Type: Animal Study, Human Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Animal offspring, Protective effect