Showing 1 to 10 of 92 Search Results:
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Systematic impacts of fluoride exposure on the metabolomics of rats.
Zhao S, Guo J, Xue H, Meng J, Xie D, Liu X, Yu Q, Zhong H, Jiang P.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: July 21, 2022
Volume/Page: 242:113888.
Type: Animal Study
Categories: Bones/Joints, Skeletal Fluorosis, Brain, Brain Cellular/Tissue Effects, Dental Fluorosis, Heart, Kidney, Liver, Mechanisms of Cellular Toxicity, Oxidative Stress, Total Body Burden, Tissue F Levels, Hippocampus, Serum-F
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Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: May 25, 2022
Volume/Page: 239:113682.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Hippocampus, Animal offspring, Developmental neurotoxicant, Neurotoxicity, Pregnant animal
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Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: April 11, 2022
Volume/Page: 236:113500.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, Autophagy, Neurotoxicity, Protective effect
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NaF-induced neurotoxicity via activation of the IL-1B/JNK signaling pathway.
Zhang C, Yang Y, Gao Y, Sun D.
Journal Name: Toxicology
Publish Date: February 13, 2022
Volume/Page: [Epub ahead of print]
Type: Cell Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, Neurotoxicity
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Evaluation of Metformin and Dehydrozingerone against fluorosis induced neurodevelopmental toxicity in preclinical models.
Ahuja T, Kumar N, Begum F, Shenoy RR.
Journal Name: Alzheimers Dementia
Publish Date: December 31, 2021
Volume/Page: Suppl 12:e058668.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Lipid peroxidation, Protective effect
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Sirt3-mediated mitochondrial dysfunction is involved in fluoride-induced cognitive deficits.
Wang D, Cao L, Pan S, Wang G, Wang L, Cao N, Hao X.
Journal Name: Food and Chemical Toxicology
Publish Date: November 12, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Neurotoxicity, Sirt3
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Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y.
Journal Name: Journal of Agricultural and Food Chemistry
Publish Date: November 4, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study, Cell Study
Categories: Brain, Behavior, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus
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Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice.
Xin J, Wang H, Sun N, Bughio S, Zeng D, Li L, Wang Y, Khalique A, Zeng Y, Pan K, Jing B, Ma H, Bai Y, Ni X.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: March 30, 2021
Volume/Page: 215:112108.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Gastrointestinal, Hippocampus, Protective effect
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Effect of dexmedetomidine on sevoflurane-induced neurodegeneration in neonatal rats.
Lee JR, Joseph B, Hofacer RD, Upton B, Lee SY, Ewing L, Zhang B, Danzer SC, Loepke AW.
Journal Name: BJA (British Journal of Anaesthesia)
Publish Date: March 12, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, anesthetics, Neurotoxicity, Sevoflurane
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Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats.
Ferreira MKM, Aragao WAB, Bittencourt LO, Puty B, Dionizio A, deSouza MPC, Buzalaf MAR, de Oliveira EH, Crespo-Lopez ME, Lima RR.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: January 15, 2021
Volume/Page: 208:111437.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Oxidative Stress, Total Body Burden, Tissue F Levels, Hippocampus, Serum-F, Animal offspring, Lipid peroxidation