Abstract

Introduction

This study aims to examine physician and dentist fluoride prescription patterns and identify the factors associated with fluoride prescriptions for Medicaid-enrolled children. The hypothesis is that dentists will be the primary prescribers of fluoride and that caries risk factors will be associated with fluoride prescriptions.

Methods

Data were analyzed for Oregon children aged 0-17 years enrolled in Medicaid for >300 days in both 2016 and 2017. The outcome variable was receiving a fluoride prescription in 2017. A 2-tailed chi-square test was used to assess fluoride prescribing differences between physicians and dentists. Multivariable logistic regression models were used to examine the likelihood of receiving a fluoride prescription in 2017 and to generate ORs. Model covariates included child’s age, sex, race, ethnicity, Medicaid plan type, previous fluoride prescription, previous restorative dental treatment, and water fluoridation status.

Results

Of 200,169 Medicaid-enrolled children, 6.7% (n=13,337) received fluoride prescriptions. Physicians were >3 times as likely to prescribe fluoride as dentists (73.4% vs 23.0%, p<0.001). Children with a history of fluoride prescriptions (OR=14.30, p<0.001) and any restorative dental treatment (OR=1.58, p<0.001) were significantly more likely to receive a fluoride prescription, whereas children living in areas with water fluoridation were significantly less likely (OR=0.50, p=0.01).

Conclusions

Physicians play an important role in prescribing fluoride to Medicaid-enrolled children, especially those at increased dental caries risk. Additional research is needed on strategies to ensure that all high-risk children have an opportunity to benefit from prescription fluoride.

REFERENCES

1. GBD 2017 Oral Disorders Collaborators • Bernabe, E • Marcenes, W …

Global, regional, and national levels and trends in burden of oral conditions from 1990 to 2017: a systematic analysis for the Global Burden of Disease 2017 Study

J Dent Res. 2020; 99:362-373

2. Herzog, K •  Scott, J •  Chi, DL …

Children’s Oral Health inequalities: intersectionality of race, ethnicity, and income

Treadwell, HM • Evans, CA (Editors)

Oral Health in America: Removing the Stain of Disparity

APHA Press, Washington, DC, 2019; 15-24

3. Colak, H • Dülgergil, CT • Dalli, M …

Early childhood caries update: a review of causes, diagnoses, and treatments

J Nat Sci Biol Med. 2013; 4:29-38

4. Chi, DL • Masterson, EE • Carle, AC …

Socioeconomic status, food security, and dental Caries in U.S. children: mediation analyses of data from the National Health and Nutrition Examination Survey, 2007-2008

Am J Public Health. 2014; 104:860-864

5. Muñoz-Millán, P • Zaror, C • Espinoza-Espinoza, G …

Effectiveness of fluoride varnish in preventing early childhood caries in rural areas without access to fluoridated drinking water: a randomized control trial

Community Dent Oral Epidemiol. 2018; 46:63-69

6. Kelly, SE •  Binkley, CJ • Neace, WP …

Barriers to care-seeking for children’s oral health among low-income caregivers

Am J Public Health. 2005; 95:1345-1351

7. Badri, P •  Saltaji, H • Flores-Mir, C …

Factors affecting children’s adherence to regular dental attendance: a systematic review

J Am Dent Assoc. 2014; 145:817-828

8. Rozier, RG • White, BA • Slade, GD.

Trends in oral diseases in the U.S. population

J Dent Educ. 2017; 81:eS97-eS109

9. Rozier, RG • Sutton, BK • Bawden, JW …

Prevention of early childhood caries in North Carolina medical practices: implications for research and practice

J Dent Educ. 2003; 67:876-885

10. Lewis, C • Teeple, E • Robertson, A …

Preventive dental care for young, Medicaid-insured children in Washington State

Pediatrics. 2009; 124:e120-e127

11. Stearns, SC • Rozier, RG • Kranz, AM …

Cost-effectiveness of preventive oral health care in medical offices for young Medicaid enrollees

Arch Pediatr Adolesc Med. 2012; 166:945-951

12. Kranz, AM • Rozier, RG • Preisser, JS …

Preventive services by medical and dental providers and treatment outcomes

J Dent Res. 2014; 93:633-638

13. Lewis, CW • Boulter, S • Keels, MA …

Oral health and pediatricians: results of a national survey

Acad Pediatr. 2009; 9:457-461

14. Sams, LD • Rozier, RG • Wilder, RS …

Adoption and implementation of policies to support preventive dentistry initiatives for physicians: a national survey of Medicaid programs

Am J Public Health. 2013; 103:e83-e90

15. Weyant, RJ • Tracy, SL • Anselmo, TT …

Topical fluoride for caries prevention: executive summary of the updated clinical recommendations and supporting systematic review

[published correction appears in J Am Dent Assoc. 2013;144(12):1335] J Am Dent Assoc. 2013; 144:1279-1291

16. Rozier, RG • Adair, S • Graham, F …

Evidence-based clinical recommendations on the prescription of dietary fluoride supplements for caries prevention: a report of the American Dental Association Council on Scientific Affairs

J Am Dent Assoc. 2010; 141:1480-1489

17. Screening and interventions to prevent dental caries in children younger than age 5 years. U.S. Preventive Services Task Force

Updated January 2, 2020

https://www.uspreventiveservicestaskforce.org/uspstf/draft-update-summary/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1

Date accessed: September 26, 2020

18. Clark, MB • Slayton, RL

Section on Oral Health. Fluoride use in caries prevention in the primary care setting

Pediatr. 2014; 134:626-633

19. Silk, H • McCallum, W

Fluoride: the family physician’s role

Am Fam Physician. 2015; 92:174-179

20. Ly, P • Hayes, DK • Yamashiroya, V …

Knowledge and attitudes towards fluoride supplementation: a survey of pediatric medical and dental providers in the state of Hawai’i

Hawaii J Med Public Health. 2018; 77:275-282

21. Roberts, MW • Keels, MA • Sharp, MC …

Fluoride supplement prescribing and dental referral patterns among academic pediatricians

Pediatrics. 1998; 101:E6

22. Kuthy, RA • McTigue, DJ.

Fluoride prescription practices of Ohio physicians

J Public Health Dent. 1987; 47:172-176

23. Herndon, JB • Tomar, SL • Lossius, MN …

Preventive oral health care in early childhood: knowledge, confidence, and practices of pediatricians and family physicians in Florida

J Pediatr. 2010; 157:1018-1024

e10242

24. 2018 Fluoridation statistics. Centers for Disease Control and Prevention. https://www.cdc.gov/fluoridation/statistics/2018stats.htm. Updated September 8, 2020. Accessed August 28, 2020.

25. Damiano, P • Momany, ET • Crall, JJ.

Determining dental utilization rates for children: an analysis of data from the Iowa Medicaid and SCHIP programs

J Public Health Dent. 2006; 66:97-103

26. NPPES NPI Registry. Centers for Medicare and Medicaid Services. https://npiregistry.cms.hhs.gov. Accessed July 21, 2020.

27. Fisher-Owens, SA • Gansky, SA • Platt, LJ …

Influences on children’s oral health: a conceptual model

Pediatrics. 2007; 120:e510-e520

28. DeVoe, JE • Graham, AS • Angier, H …

Obtaining health care services for low-income children: a hierarchy of needs

J Health Care Poor Underserved. 2008; 19:1192-1211

29. State ‘accountable care’ activity map. National Academy for State Health Policy. https://www.nashp.org/state-accountable-care-activity-map/. Accessed December 23, 2020.

30.

Coordinated care organizations (CCO). Oregon Health Authority, Oregon Health Plan. https://www.oregon.gov/oha/hsd/ohp/pages/coordinated-care-organizations.aspx. Accessed December 23, 2020.

31. Coordinated care: the Oregon difference. Oregon Health Authority, Health Policy and Analytics. https://www.oregon.gov/oha/HPA/Pages/CCOs-Oregon.aspx. Accessed December 23, 2020.

32. Chi, DL • Momany, ET • Neff, J …

Impact of chronic condition status and severity on dental utilization for Iowa Medicaid-enrolled children

Med Care. 2011; 49:180-192

33. My water’s fluoride. Centers for Disease Control and Prevention. https://nccd.cdc.gov/DOH_MWF/Default/Default.aspx. Accessed July 21, 2020.

34. Oregon ZIP codes. Zipcodes.com. https://www.zipcodes.com/state/or.asp. Accessed July 21, 2020.

35. Barnard, J • Meng, XL.

Applications of multiple imputation in medical studies: from AIDS to NHANES

Stat Methods Med Res. 1999; 8:17-36

36. Bounthavong, M • Watanabe, JH • Sullivan, KM.

Approach to addressing missing data for electronic medical records and pharmacy claims data research

Pharmacotherapy. 2015; 35:380-387

37. Janssen, KJ • Donders, AR • Harrell, Jr, FE …

Missing covariate data in medical research: to impute is better than to ignore

J Clin Epidemiol. 2010; 63:721-727

38. Jakobsen, JC • Gluud, C • Wetterslev, J …

When and how should multiple imputation be used for handling missing data in randomised clinical trials – a practical guide with flowcharts

BMC Med Res Methodol. 2017; 17:162

39. Madley-Dowd, P • Hughes, R • Tilling, K …

The proportion of missing data should not be used to guide decisions on multiple imputation

J Clin Epidemiol. 2019; 110:63-73

40. Kranz, AM • Preisser, JS • Rozier, RG.

Effects of physician-based preventive oral health services on dental caries

Pediatrics. 2015; 136:107-114

41. Narendran, S • Chan, JT • Turner, SD …

Fluoride knowledge and prescription practices among dentists

J Dent Educ. 2006; 70:956-964

42. Silk, H • Kwok, A.

Addressing adolescent oral health: a review

Pediatr Rev. 2017; 38:61-68

43. Sohn, W • Ismail, AI • Taichman, LS.

Caries risk-based fluoride supplementation for children

Pediatr Dent. 2007; 29:23-31

44. Lynch, RJ.

The primary and mixed dentition, post-eruptive enamel maturation and dental caries: a review

Int Dent J. 2013; 63:3-13

45. Pahel, BT • Rozier, RG • Stearns, SC …

Effectiveness of preventive dental treatments by physicians for young Medicaid enrollees

Pediatrics. 2011; 127:e682-e689

46. Kobayashi, M • Chi, DL • Coldwell, SE …

The effectiveness and estimated costs of the access to baby and child dentistry program in Washington State

J Am Dent Assoc. 2005; 136:1257-1263

47. Irvine, J • Holve, S • Krol, D …

Early childhood caries in Indigenous communities: a joint statement with the American Academy of Pediatrics

Paediatr Child Health. 2011; 16:351-364

48. Caries-risk assessment and management for infants, children, and adolescents

Pediatr Dent. 2017; 39:197-204

49. Chi, DL.

Parent refusal of topical fluoride for their children: clinical strategies and future research priorities to improve evidence-based pediatric dental practice

Dent Clin North Am. 2017; 61:607-617

50. Curiel, JA • Slade, GD • Christian, TL …

Referendum opposition to fluoridation and health literacy: a cross-sectional analysis conducted in three large U.S. cities

BMJ Open. 2019; 9, e022580

51. Kalenderian, E • Ramoni, RL • White, JM …

The development of a dental diagnostic terminology
J Dent Educ. 2011; 75:68-76