Showing 11 to 20 of 279 Search Results:
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Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: April 11, 2022
Volume/Page: 236:113500.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, Autophagy, Neurotoxicity, Protective effect
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NaF-induced neurotoxicity via activation of the IL-1B/JNK signaling pathway.
Zhang C, Yang Y, Gao Y, Sun D.
Journal Name: Toxicology
Publish Date: February 13, 2022
Volume/Page: [Epub ahead of print]
Type: Cell Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, Neurotoxicity
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Evaluation of Metformin and Dehydrozingerone against fluorosis induced neurodevelopmental toxicity in preclinical models.
Ahuja T, Kumar N, Begum F, Shenoy RR.
Journal Name: Alzheimers Dementia
Publish Date: December 31, 2021
Volume/Page: Suppl 12:e058668.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Lipid peroxidation, Protective effect
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Impacts of Fluoride Neurotoxicity and Mitochondrial Dysfunction on Cognition and Mental Health: A Literature Review.
Adkins EA and Brunst KJ.
Journal Name: International Journal of Environmental Research and Public Health
Publish Date: December 7, 2021
Volume/Page: 18(24):12884;
Type: Review
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Susceptible Populations, Age, Autophagy, mitochondrial dysfunction, Neurotoxicity, Prenatal exposure
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Sirt3-mediated mitochondrial dysfunction is involved in fluoride-induced cognitive deficits.
Wang D, Cao L, Pan S, Wang G, Wang L, Cao N, Hao X.
Journal Name: Food and Chemical Toxicology
Publish Date: November 12, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, mitochondrial dysfunction, Neurotoxicity, Sirt3
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Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y.
Journal Name: Journal of Agricultural and Food Chemistry
Publish Date: November 4, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study, Cell Study
Categories: Brain, Behavior, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus
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DNA methylation and fluoride exposure in school-age children: Epigenome-wide screening and population-based validation.
Wang A, Ma Q, Gong B, Sun L, Afrim FK, Sun R, He T, Huang H, Zhu J, Zhou G, Ba Y.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: August 6, 2021
Volume/Page: 223:112612.
Type: Human Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, DNA effects, Susceptible Populations, Age, Genetics, Total Body Burden, Tissue F Levels, Urine-F, Neurotoxicity
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Human cultured IMR-32 neuronal-like and U87 glial-like cells have different patterns of toxicity under fluoride exposure.
Puty B, Bittencourt LO, Nogueira IC, Buzalaf MAR, Oliveira EH, Lima RR.
Journal Name: PLoS One
Publish Date: June 17, 2021
Volume/Page: 16(6):e0251200
Type: Cell Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, DNA effects
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Fluoride exposure decreased neurite formation on cerebral cortical neurons of SD rats in vitro.
Ning H, Li C, Yin Z, Hu D, Ge Y, Chen L.
Journal Name: Environmental Science and Pollution Research
Publish Date: May 11, 2021
Volume/Page: [Epub ahead of print]
Type: Cell Study
Categories: Brain, Brain Cellular/Tissue Effects, Neurotoxicity
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Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice.
Xin J, Wang H, Sun N, Bughio S, Zeng D, Li L, Wang Y, Khalique A, Zeng Y, Pan K, Jing B, Ma H, Bai Y, Ni X.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: March 30, 2021
Volume/Page: 215:112108.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Gastrointestinal, Hippocampus, Protective effect