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The effect of fluoride on bone
| The Proceedings of the Nutrition Society | Weidmann SM, Weatherell JA, Jackson D. | 22:105-10.
Bone Mineralization/Quality Bone-F Bones/Joints Skeletal Fluorosis Tissue F Levels Total Body Burden Human Study
Conclusions Although it is well known that the ingestion of high levels of fluoride can give rise to severe lesions in the skeletal tissues, such effects have never been found radiographically in persons using a water supply, containing less than 4 p.p.m fluorlde throughout life. A histological study of thirty ribs taken from deceased residents of a region where the drinking water contained 1.9 p.p.m. fluoride revealed no changes characteristic of skeletal fluorosis. Although even at a level

Excerpt:

Conclusions

Although it is well known that the ingestion of high levels of fluoride can give rise to severe lesions in the skeletal tissues, such effects have never been found radiographically in persons using a water supply, containing less than 4 p.p.m fluorlde throughout life.

A histological study of thirty ribs taken from deceased residents of a region where the drinking water contained 1.9 p.p.m. fluoride revealed no changes characteristic of skeletal fluorosis.

Although even at a level of 1 p.p.m. fluoride in the drinking water, the concentration of the element in bone increases with age, the level reached after lifelong ingestion of water containing 1 p.p.m. fluoride would be appreciably lower than that associated with the condition of skeletal fluorosis.