Tag: anesthetics

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Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice

March 30, 2021

References 1. Bayer SA, Altman J, Russo RJ, Zhang X: Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology 1993; 14:83–144. 2. Rice D, Barone S Jr: Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models. Environ Health Perspect 2000; 108:511–33. 3. […]

Effect of dexmedetomidine on sevoflurane-induced neurodegeneration in neonatal rats.

March 30, 2021

References Lin E.P., Lee J.R., Lee C.S., Deng M., Loepke A.W. Do anesthetics harm the developing human brain? An integrative analysis of animal and human studies. Neurotoxicol Teratol. 2017; 60: 117-128. PubMed Jevtovic-Todorovic V., Olney J.W. PRO: anesthesia-induced developmental neuroapoptosis: status of the evidence. Anesth Analg. 2008; 106: 1659-1663. PubMed Loepke A.W. McGowan Jr., F.X. […]