Tag: anesthetics
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The Abortive Lives of Modern Inhalation Anesthetics.
READERS of this periodical were probably intrigued when, in 1971, almost an entire issue was devoted to studies in volunteers of a new anesthetic, isoflurane (Forane), a novel and useful editorial departure. Since then, a series of reports in the Journal has cast further light on some of the more arcane properties of this heavily […]
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Fate of fluorinated metabolites of inhalation anesthetics in man.
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Neurotoxicity in operating room personnel working with gaseous and nongaseous anesthesia.
Excerpt Introduction According to experimental and field studies, exposure to more than 500 ppm of nitrous oxide(N 2O) and more than 15 ppm of haJothane and enflurane can cause performance impairment in neurobehavioral exammations (Bruce and Bach 1975, 1976; Smith and Shirley 1978; Allison et al. 1979; Edling 1980; Mahoney et al. 1988. Control of […]
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Fluoride concentrations in urine of delivery ward personnel following exposure to low concentrations of methoxyflurane.
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Serum fluoride levels following commencement of methoxyflurane for patient analgesia in an ambulance service.
Editor—Methoxyflurane, once a frequently used anaesthetic agent,1 is re-emerging as an inhalation analgesic. In modern practice, it is given in doses of up to 6 mL via a proprietary patient-controlled self-delivery device2 with an activated carbon filter designed to adsorb some methoxyflurane vapour from the patient’s exhaled breath.3 Methoxyflurane is an organic vapour, identified as […]
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The impact of sevoflurane anesthesia on postoperative renal function: a systematic review and meta-analysis of randomized-controlled trials.
References Abbvie Ltd. ULTANE® (sevoflurane) volatile liquid for inhalation. Available from URL: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020478s030lbl.pdf (accessed June 2020). Mazze RI. Methoxyflurane revisited: tale of an anesthetic from cradle to grave. Anesthesiology 2006; 105: 843-6. CAS PubMed Google Scholar Gentz BA, Malan TP Jr. Renal toxicity with sevoflurane: a storm in a teacup? Drugs 2001; 61: 2155-62. CAS […]
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The future is now—it’s time to rethink the application of the Global Warming Potential to anesthesia
All volatile anesthetic agents are fluorocarbons and variably potent greenhouse gases (GHG).1 As a chlorofluorocarbon (CFC), isoflurane also has ozone depleting potential (as does nitrous oxide [N2O]), while sevoflurane and desflurane, being hydrofluorocarbons (HFC), do not.1 The global emission of HFCs increased 128% from 1990 to 2005 and is projected by 2030 to increase a […]
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Effect of inhaled waste anaesthetic gas on blood and liver parameters among hospital staff.
References 1. Miller, RD, Erikson, LI, Fleisher, LA, et al. Miller’s anesthesia. 7th ed. Philadelphia: Churchill Livingstone Elsevier, 2010. Google Scholar | Crossref 2. Lee, JH . Anesthesia for ambulatory surgery. Korean J Anesthesiol 2017; 70(4): 398–406. Google Scholar | Crossref | Medline 3. Özelsel1, TJ, Kim, S, Buro, K, et al. Elevated waste anaesthetic […]
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Teratogenicity caused by halothane, enflurane, and sevoflurane, and changes depending on O2 concentration.
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Cancer and Other Outcomes After Surgery With Fluoridated Anesthesia