Tag: FEX
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Nitrate and phosphate transporters rescue fluoride toxicity in yeast.
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Fluoride export (FEX) proteins from fungi, plants and animals are ‘single barreled’ channels containing one functional and one vestigial ion pore.
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Yeast Fex1p Is a Constitutively Expressed Fluoride Channel with Functional Asymmetry of Its Two Homologous Domains.
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Structural introspection of a putative fluoride transporter in plants.
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Heterologous transporters from anaerobic fungi bolster fluoride tolerance in Saccharomyces cerevisiae.
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Impairing fluoride export of Aspergillus fumigatus mitigates its voriconazole resistance.
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CsFEX, a fluoride export protein gene from Camellia sinensis, alleviates fluoride toxicity in transgenic Escherichia coli and Arabidopsis thaliana.
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Eukaryotic resistance to fluoride toxicity mediated by a widespread family of fluoride export proteins
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Small molecule fluoride toxicity agonists
INTRODUCTION Although fluoride is commonly added to oral hygiene products to increase the strength of tooth enamel, it also has substantial anti-bacterial effects (Barbier et al., 2010; Li, 2003). For example, when in complex with a divalent metal ion and ADP, fluoride forms a nonfunctional mimic of ATP that can inhibit enolase (Curran et al., […]