The link between ancient microbial fluoride resistance mechanisms and bioengineering organofluorine degradation or synthesis. May 30, 2024
The fluoride permeation pathway and anion recognition in Fluc family fluoride channels. July 13, 2021 Introduction Microbes are protected from the cytoplasmic accumulation of environmental fluoride ion by export of the toxic anion via fluoride channels known as Flucs [1-3]. These small, homodimeric ion channels are remarkable proteins in two regards: first, their unusual “dual topology” architecture, in which the two subunits of the homodimer are arranged antiparallel with respect […]
An Interfacial Sodium Ion is an Essential Structural Feature of Fluc Family Fluoride Channels. July 23, 2020
Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies. May 15, 2019