Tag: mother-offspring
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A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
Discussion … The increased precision using the average maternal U-F concentration as an indicator of prenatal fluoride exposure results in stronger statistical evidence of fluoride-associated deficits, compared with using cross-sectional or retrospective studies. Still, the amount of fluoride that reaches the brain during early brain development is unknown, and even the maternal U-F concentration measurements […]
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Critical Windows of Fluoride Neurotoxicity in Canadian Children.
Discussion We used data from a prospective pregnancy and birth cohort to compare the associations between fluoride exposures during different developmental windows and preschool aged children’s intellectual abilities. The GEE method advances our understanding of early-life fluoride neurotoxicity by formally comparing strength of associations across windows of exposure. The strongest association between fluoride and child […]
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Cohort profile: the maternal-infant research on environmental chemicals research platform.
Online here Background: The Maternal-Infant Research on Environmental Chemicals (MIREC) Study was established to obtain Canadian biomonitoring data for pregnant women and their infants, and to examine potential adverse health effects of prenatal exposure to priority environmental chemicals on pregnancy and infant health. Methods: Women were recruited during the first trimester from 10 sites across […]
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A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
This article is a preprint and has not been peer-reviewed. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. Abstract As a safe exposure level for fluoride in pregnancy has not been established, we used data from two prospective studies for benchmark dose […]
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Are low fluoride levels in drinking water really detrimental for neuropsychological neurodevelopment in childhood?
Authors: J. Ibarluzea, Department of Health of the Basque Government, Subdirectorate of Public Health of Gipuzkoa, Donostia-San Sebastián, SPAIN M. Gallastegi, Biodonostia Health Research Institute, Group of Environmental Epidemiology and Child Development., Donostia-San Sebastián, SPAIN M. Lopez Espinosa, Nursing School, Universitat de Valencia, Valencia, SPAIN C. M. Villanueva, Spanish Consortium for Research on Epidemiology and […]
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Trimester Specific Association of Prenatal Fluoride Exposure and Cognitive Outcomes in Children in Mexico.
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Fluoride concentration in amniotic fluid and fetal cord and maternal plasma.
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Umbilical cord fluoride serum levels may not reflect fetal fluoride status.
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Is Fluoride Potentially Neurotoxic?
An Editorial by David C. Bellinger, PhD, MSc Environmental epidemiology is a field replete with controversies, but the intensity of the debate inspired by the fluoridation of municipal water supplies to reduce dental caries is perhaps unrivaled. Governments, as well as individuals, differ in their assessments of water fluoridation as public policy. The US Centers […]
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Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada.
Key Points Question Is maternal fluoride exposure during pregnancy associated with childhood IQ in a Canadian cohort receiving optimally fluoridated water? Findings In this prospective birth cohort study, fluoride exposure during pregnancy was associated with lower IQ scores in children aged 3 to 4 years. Meaning Fluoride exposure during pregnancy may be associated with adverse […]