Tag: Neurotoxicity
Showing 10 of 85:
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Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
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ERK1/2-mediated disruption of BDNF–TrkB signaling causes synaptic impairment contributing to fluoride–induced developmental neurotoxicity
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The Influence of Fluorine on the Disturbances of Homeostasis in the Central Nervous System.
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Low Prenatal Exposures to Fluoride: Are There Neurotoxic Risks for Children?
As a trace element, fluoride can help ward off dental cavities. Exceptionally high pre- and postnatal exposures, as seen in populations whose drinking water supplies are contaminated by natural fluoride sources, have been implicated in a number of adverse health effects.1,2,3,4 However, less is known about fluoride’s neurotoxic risks at lower levels of exposure. A […]
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Histopathological investigation of fluoride-induced neurotoxicity in rabbits.
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An Evaluation of Neurotoxicity Following Fluoride Exposure from Gestational Through Adult Ages in Long-Evans Hooded Rats.
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Chronic treatment with fluoride affects the jejunum: insights from proteomics and enteric innervation analysis.
EXCERPTS … Generally, many studies report Rab proteins as molecules present in the CNS and their specific roles. Although marked differences distinguish the neuronal function between the ENS [Enteric Nervous System] and CNS, their similarities allow the use of some principles established for the brain environment to be reapplied in the enteric context 38. Several […]
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The effect of the fluoride ion on reproductive parameters and an estimate of the safe daily dose of fluoride to prevent female infertility and miscarriage, and foetal neurotoxicity.
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The protective properties of selected naturally occurring antioxidants of plant origin against fluoride-induced neurotoxicity.
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Neurotoxicity induced by fluoride in rat cerebral cortex
In cerebral cortex of the rats, treated with 100 ppm of sodium fluoride, there was disorganization of granular cell layer. The granule cells were accumulated in the form of clumps. Some pyramidal neurons showed chromatolysis (Fig. 2) and were shrunken with vacuolation around them (Fig. 4). The nuclei of some pyramidal neurons were eccentric in […]