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Tag: Pharmaceuticals

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Voriconazole-Associated Periostitis: New Insights into Pathophysiology and Management.

March 3, 2022

1. Introduction Voriconazole is a frequently used antifungal in the post-transplant setting and has been associated with periostitis with long-term use.( 1 ) The true prevalence of voriconazole-associated periostitis (VAP) is unknown; however, retrospective studies suggest this adverse effect may occur in up to 15% of patients on voriconazole.( 1 , 2 , 3 ) […]

Chemical Aspects of Human and Environmental Overload with Fluorine

March 17, 2021

Optimal trough concentration of voriconazole with therapeutic drug monitoring in children: A systematic review and meta-analysis.

March 15, 2021

Metabolism and Toxicity of Fluorine Compounds

March 15, 2021

Abstract Fluorine has many beneficial features and applications but can cause toxicity at high doses. Herein, we describe its chemical properties and benefits to agrochemical design as well as potential metabolic liabilities and exposure assessment in vivo. The use of fluorine in drugs and agricultural chemicals has greatly expanded since the first fluoro compound, […]

Fluorosis by the Ministry of Health & Family Welfare, National Health, India.

February 20, 2019

Flutemetamol F 18. Summary of Use during Lactation.

July 15, 2018

Drug Levels and Effects Information in this record refers to the use of flutemetamol F 18 as a diagnostic agent. No information is available on the use of flutemetamol F 18 during breastfeeding. The manufacturer recommends withholding breastfeeding for 24 hours after a diagnostic dose of 185 MBq (5 mCi). This length of time is […]

Florbetaben F 18: Summary of Use during Lactation.

July 15, 2018

Drug Levels and Effects Information in this record refers to the use of florbetaben F 18 as a diagnostic agent. No information is available on the use of florbetaben F 18 during breastfeeding. The manufacturer recommends withholding breastfeeding for 24 hours after a diagnostic dose Twenty-four hours is about 10 half-lives of fluoride F 18 […]

A case of skeletal fluorosis? (Letter)

June 27, 2018

A 79-year-old lady presented with a history of diffuse sero-negative arthritis dating from early adulthood. Numerous investigations and therapies had failed to provide any significant benefit and both knees and a hip had been replaced when initially seen a year ago. On questioning at that time, she admitted to daily drinking at least six cups […]

Elevated fluoride levels and periostitis in pediatric hematopoietic stem cell transplant recipients receiving long-term voriconazole

October 22, 2014

Perioral dermatitis

February 21, 2014

Since its description in 1957 by Frumess and Lewis (1) as a “light-sensitive seborrheid,” perioral dermatitis (PD) has been a perplexing entity. It characteristically presents as a chronic eruption consisting of papules and pustules that develop on irregular areas of erythema and edema. the eruption is most prominent in the perioral area, but occasionally it […]

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