Highlights Evidence of poisoning with organophosphorus (OP) nerve agents requires biomedical verification. OP nerve agents undergo common biotransformation pathways producing valuable biomarkers. Internationally accepted methods target remaining poison, hydrolysis products and protein-adducts. Mass spectrometry-based methods provide optimum selectivity and sensitivity for identification. Methods, strategies, current proceedings, quality criteria and real cases of poisoning are presented. […]
Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification.
December 4, 2021