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Revisiting Fluoride in the Twenty-First Century: Safety and Efficacy Considerations.
Conclusions In this manuscript, we present a simple graphical plot/tabular tool which allows clinicians to gauge the overall exposure of their patients to fluoride-containing products with respect to both acute and chronic toxicities. This tool will undoubtedly also assist clinicians who wish to discuss these issues with adult patients, and parents of child patients, about […]
Metabolism and Toxicity of Fluorine Compounds
Abstract Fluorine has many beneficial features and applications but can cause toxicity at high doses. Herein, we describe its chemical properties and benefits to agrochemical design as well as potential metabolic liabilities and exposure assessment in vivo. The use of fluorine in drugs and agricultural chemicals has greatly expanded since the first fluoro compound, […]