Mipafox
CAS No. 371-86-8

 
 

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Adverse Effects
Abstracts

ACTIVITY: Acaricide, Insecticide (organophosphate)

Note: WHO: Believed to be obsolete or discontinued for use as pesticides.

CAS Name: N,N?-bis(1-methylethyl)phosphorodiamidic fluoride

Structure:

Adverse Effects:

Ataxia
Brain
CNS
Sciatic Nerve
Spinal Cord

Environmental Effects:

Long half life in water at PH6 (200 days)

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No 
US EPA PC Code: 356300 
Other Information
Molecular Formula: C6H16 F N2OP  
Manufacturers: Aventis 
Other Names: 
Systematic Name
Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)- (9CI)
Phosphorodiamidic fluoride, N,N'-diisopropyl-
Synonyms
4-04-00-00536 (Beilstein Handbook Reference)
BRN 1705911
Bis(isopropylamido) fluorophosphate
Bis(isopropylamido)fluorophosphate
Bis(monoisopropylamino)fluorophosphate
Bis(monoisopropylamino)fluorophosphine oxide
Bisisopropylaminofluorophosphine oxide
Caswell No. 356B
Di(isopropylamido)phosphoryl fluoride
EINECS 206-742-3
Fluorobisisopropylaminophosphine oxide
Fluorure de N,N'-diisopropyle phosphorodiamide [French]
HSDB 1585
Isopestox
N,N'-Diisopropil-fosforodiammido-fluoruro [Italian]
N,N'-Diisopropyl-diamido-fosforzuur-fluoride [Dutch]
N,N'-Diisopropyl-diamido-phosphorsaeure-fluorid [German]
N,N'-Diisopropyldiamidophosphoryl fluoride
N,N'-Diisopropylphosphorodiamidic fluoride
NSC 8924
Peston XV
Pestox 15
Pestox XV
Phosphine oxide, fluorobis(isopropylamino)-
Phosphorodi(isopropylamidic) fluoride
Phosphorodiamidic fluoride, N,N'-bis(1-methylethyl)-
Phosphorodiamidic fluoride, N,N'-diisopropyl-
Of special interest:
PAN Data 
TOXNET profile from Hazardous Substances Data Base 
Organophosphate Toxicity. Mipafox is a selective systemic insecticide which is absorbed into the plant sap and remains active for long periods of time. Mipafox causes demyelination in peripheral nerves, causing lesions which resemble those due to thiamine deficiency. Michigan Wildlife Diseases Manual.
Delayed Toxic Effects of Chemical Warfare Agents - Monograph by the Stockholm International Peace Research Institute (SIPRI)
Referenced in article on Sarin used in the Gulf War 
Abstracts 
Believed to be obsolete or discontinued for use as pesticides. WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2000-2002. Table 6. Active ingredients not included in the Classification and believed to be obsolete or discontinued for use as pesticides, p 37.  
Organophosphorus Insecticide Poisoning - JIFCC 1999, Volume 11, No. 2
CHEMWATCH Rating: Extreme Toxicity 
 
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