Abstract
In the electrocardiogram of rabbits given sodium fluoride orally, a pattern of myocardial damage was observed, namely depressed ST, inverted T, prolonged QT interval, multifocal ventricular premature contraction, bundle branch block, and pulmonary P. Histologically, regressive degeneration, cellular infiltration, hyperemia, hemorrhages and thickening of vessel wall were noted in the heart muscle.
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[Experimental study on rat cardiac toxicity induced by sodium fluoride of different dosages].
The cardiotoxic effect of various dosage of sodium fluoride was investigated. Three-week-old male Wistar rats were fed on normal fodder and distilled water containing different dosages (0, 25, 50, 100 and 150 mg/litre) of sodium fluoride for 6 months to establish an animal model of chronic fluorosis. Electrocardiogram (ECG) was
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Effects of chronic fluorosis on electrocardiogram in dogs
The aim of this study was to determine the effects of chronic fluorosis on the electrocardiogram (ECG) in dogs. A total of sixteen mixed breed dogs (8 fluorotic and 8 healthy), 2 to 3 years old and weighing 18–30 kg, were used in this study. The eight dogs with chronic
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Electrocardiogram analysis of patients with skeletal fluorosis
To investigate the degree of myocardial damage resulting from endemic fluorosis, electrocardiograms of 136 skeletal fluorosis patients from an endemic fluorosis area were compared with electrocardiograms of a control group of 40 normal patients from a non-endemic fluorosis area. The results show that fluoride in drinking water consumed over time
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Changes of the heart muscle due to chronic fluorosis. Part 1: Electrocardiogram and cardiac x-rays in inhabitants of a high fluoride zone
1) The author examined inhabitants of a high fluoride zone (Shionoe village, Kagawa Prefecture, and Odani villAge, Sanyo town, Okayama Prefecture). ln residents of these zones , greater myocardial damage was detected electrocardiographically and dilatation of the cardiac sillouette roentgenograpbically than in n0n-fluoride areas. 2) The myocardial damage appears to
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Observations on electrocardiograms in a population living in a region with coal-burning-borne endemic fluorosis after comprehensive controls
Objective: To observe the electrocardiogram (ECG) changes in the population living in the region with coal-burning-borne endemic fluorosis (EF for short) after comprehensive controls. Methods: People living in a region with coal-burning-borne EF in Bijie City of Guizhou Province were selected and then divided into 4 groups according to the
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Fluoride & Arteriosclerosis
Healthy arteries are flexible and elastic, allowing efficient transfer of blood and nutrients from the heart to the rest of the body. Arteriosclerosis refers to a stiffening of the arteries, including loss of elasticity. This is a slow, progressive disease that may begin early in life from damage to the
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Fluoride & Myocardial Damage
Structural damage to the heart resulting from fluoride toxicity has been observed in numerous human and animal studies. The general features of this damage include cloudy swelling, vacuolization or vacuolar degeneration, hemorrhages, interstitial edema, fibrous necrosis, dissolution of nuclei, and thickening of the vessel walls in the heart muscle (Basha
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Fluoride & Electrocardiogram Abnormalities
An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems
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Fluoride, Blood Pressure and Hypertension
Individuals with blood pressure readings that exceed 140/90 are considered hypertensive. Hypertension can increase the risk of stroke, heart attack, heart failure, aortic aneurysms, and peripheral arterial disease. An association between increased fluoride in ground water and increased prevalence of hypertension has been observed, especially among adult males (Amini et
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Fluoride & Arterial Calcification
The major change involved with cardiovascular disease is development of atherosclerosis in critical arteries, which is partially characterized by vascular calcification. The level of coronary artery calcification is thought to be the most important indicator of future cardiovascular events. Increased arterial calcifications have frequently been reported in those with skeletal fluorosis
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