Abstract
OBJECTIVE: Prolonged excessive intake of fluoride during child’s growth and development stages has been associated with mental and physical problems. The aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (IQ) of children living in five rural areas in Makoo/Iran.
MATERIALS AND METHODS: In this cross-sectional study, 293 children aged 6-11 years were selected from five villages in Makoo with normal fluoride (0.8±0.3 ppm), medium fluoride (3.1±0.9 ppm) and high fluoride (5.2±1.1 ppm) in their water supplies. The IQ of each child was measured by the Raven’s test. Educational and residential information and the medical history of each child was recorded by a questionnaire completed by the parents. Data were analyzed by ANOVA test with a significance level of 0.05.
RESULTS: The mean IQ scores decreased from 97.77±18.91 for the normal fluoride group to 89.03±12.99 for the medium fluoride group and to 88.58±16.01 for the high fluoride group (P=0.001).
CONCLUSION: Children residing in areas with higher than normal water fluoride levels demonstrated more impaired development of intelligence. Thus, children’s intelligence may be affected by high water fluoride levels.
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The effects of high fluoride on the level of intelligence of primary and secondary students.
The harm of long-term intake of excessive fluoride on the human skeletal system has been proved. There are also reports about the effects of high fluoride on the human nervous system and mental development [1, 2]. Some studies have proved that if the mother has taken in an excessively high amount of fluoride, she can
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A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
This article is a preprint and has not been peer-reviewed. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. Abstract As a safe exposure level for fluoride in pregnancy has not been established, we used data from two prospective studies
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Investigation of intelligence quotient in 9-12-year-old children exposed to high- and low-drinking water fluoride in west Azerbaijan province, Iran
In order to investigate the relationship between fluoride (F) in drinking water and children’s intelligence quotient (IQ), 39 9–12-year-old children in West Azerbaijan, were selected and their IQ measured using the Iranian version of the RB Cattell test. The study cases were 19 children living in a high-drinking water F
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Effect of high fluoride water on intelligence of school children in India.
The intelligence quotient (IQ) was measured in 190 school-age children, 12–13 years old, residing in two village areas of India with similar educational and socioeconomic conditions but differing in fluoride (F) concentration in the drinking water. The children in the high F area (drinking water F 5.55±0.41 mg/L) had higher
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The effects of high levels of fluoride and iodine on intellectual ability and the metabolism of fluoride and iodine.
The authors carried out a study on the intellectual abilities and fluoride/iodine metabolism of children living in a high fluoride-high iodine area. Among the results: the percentage of the general population living in this fluoride/iodine-contaminated region that suffered from goiter (clinical thyroid enlargement) was 3.8%, the rate of children already showing some thyroid
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Fluoride & IQ: 76 Studies
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are 78 studies reporting reduced IQ (75 studies with children and 3 studies with adults) and several on the impaired learning/memory in animals. And there are studies which link
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
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