Abstract
Objective: To probe into the clinical and imaging manifestations and mechanisms of fluorosis-associated arthropathy.
Methods: Analyses were conducted on the clinical manifestations, X-rays and magnetic resonance examinations in 18 cases with fluorosis-associated arthropathy.
Results: Skeletal fluorosis of different severities was revealed in the 18 cases. Major clinical symptoms were as follows: pain over the spine, joints of extremities and muscles near the spine and around such joints, lumbago and leg pain being foremost, along with limitation of joint motion, joint dysfunction and even joint rigidity, plus possible joint deformity and curvature of spine. Major imaging manifestations of fluorosis-associated arthropathy included synovial thickening, joint capsule swelling, effusion in joint cavity, joint space widening, calcification of articular cartilage and consequential joint space narrowing, along with erosion, destruction and fuzziness of osseous joint surface or arthrosclerosis, [the formation of] isolated bodies in joint cavity, hyperosteogeny of joint edges, calcification of ligaments around joints, calcification of joint capsule and even fuzzy joint space.
Conclusion: The clinical and imaging manifestations of fluorosis-associated arthropathy are of certain referential value for fluorosis typing and grading.
Translation by Trans Perfect Translations (2014)
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Skeletal fluorosis in relation to drinking water, nutritional status and living habits in rural areas of Maharashtra, India
The present study was carried out during May 2010 to December 2011 in three villages which were randomly selected from Warora tehsil of Chandrapur district which is one of the endemic district of Maharashtra. . . . All the presently available ground water samples were collected and the mean fluoride concentration
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[Etiology and treatment of postoperative spinal cord injury for patients undergoing laminectomy for fluorosis thoracic canal stenosis].
OBJECTIVE: To elucidate the etiology of postoperative spinal cord injury (PSCI) for patients undergoing laminectomy for fluorosis thoracic canal stenosis (FTCS) and summarize the methods of diagnosis and treatment. METHODS: From 2006 to 2009, a total of 192 FTCS cases underwent laminectomy. Among them, 16 cases with gradual postoperative neural deterioration were finally
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On the association of fluorosis with degenerative-dystrophic lesions of the skeleton in workers engaged in electrolytic departments of aluminum plants
Workers of electrolytic departments at the Novokuznetsk aluminum plant were found to suffer not only from fluorosis (28.2) per cent), but also from degenerative-dystrophic affection of the skeleton (87.7 per cent). The workers of a control group who were not exposed to a chronic action of fluorine compounds the degenerative-dystrophic
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Why did the ancient inhabitants of Palmyra suffer fluorosis?
The skeletal remains uncovered from the 2nd and 3rd century underground tombs of Palmyra, Syria, retain traces of arthritis and mottled enamel. A brown discoloration was also observed in the teeth. In order to clarify that these facts can be related to fluorosis, the teeth excavated from Tomb C and
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[Generalized osteopathy with pathological fractures in a patient with long-term exposure to fluorine-containing plastics].
In a 68-year-old man with a painful syndrome of the lower extremities which began at the age of 64 years, workup revealed a generalized osteopathy with sclerosis of the axial skeleton and osteopenia at the extremities associated with pathologic fractures. The occupational history showed exposure to several synthetics such as
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Fluoride & Osteoarthritis
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Skeletal Fluorosis: The Misdiagnosis Problem
It is a virtual certainty that there are individuals in the general population unknowingly suffering from some form of skeletal fluorosis as a result of a doctor's failure to consider fluoride as a cause of their symptoms. Proof that this is the case can be found in the following case reports of skeletal fluorosis written by doctors in the U.S. and other western countries. As can be seen, a consistent feature of these reports is that fluorosis patients--even those with crippling skeletal fluorosis--are misdiagnosed for years by multiple teams of doctors who routinely fail to consider fluoride as a possible cause of their disease.
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"Pre-Skeletal" Fluorosis
As demonstrated by the studies below, skeletal fluorosis may produce adverse symptoms, including arthritic pains, clinical osteoarthritis, gastrointestinal disturbances, and bone fragility, before the classic bone change of fluorosis (i.e., osteosclerosis in the spine and pelvis) is detectable by x-ray. Relying on x-rays, therefore, to diagnosis skeletal fluorosis will invariably fail to protect those individuals who are suffering from the pre-skeletal phase of the disease. Moreover, some individuals with clinical skeletal fluorosis will not develop an increase in bone density, let alone osteosclerosis, of the spine. Thus, relying on unusual increases in spinal bone density will under-detect the rate of skeletal fluoride poisoning in a population.
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Fluoride Content of Tea
Tea, particularly tea drinks made with lower quality older leaves, contain high levels of fluoride. Because of these high levels, research has found that individuals who drink large amounts of tea can develop skeletal fluorosis -- a painful bone disease caused by excessive fluoride intake. Since skeletal fluorosis is often misdiagnosed by
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Variability in Radiographic Appearance of Skeletal Fluorosis
Osteosclerosis (dense bone) is the bone change typically associated with skeletal fluorosis, particularly in the axial skeleton (spine, pelvis, and ribs). Research shows, however, that skeletal fluorosis produces a spectrum of bone changes, including osteomalacia, osteoporosis, exostoses, changes resulting from secondary hyperparathyroidism, and combinations thereof. Although the reason for this radiographic variability is not yet fully understood, it is believed to relate to the dose of fluoride consumed, the individual's nutritional status, exposure to aluminum, genetic susceptibility, presence of kidney disease, and area of the skeleton examined.
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