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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Multiple painless masses: periostitis deformans secondary to fluoride intoxication

April 2014 | Skeletal Radiology | Chitkara M, Rackoff PJ, Beltran LS. | 43(4):529-30, 555-6.
Diagnosis The differential diagnosis based on the imaging findings included ossification of subperiosteal hematomas, ectopic calcification in the setting of a connective tissue disorder, and periostitis deformans secondary to fluoride intoxication. Laboratory assays were requested by the patient’s rheumatologist, which were notable for a mildly elevated alkaline phosphatase level (216 U/L, reference range=40–115 U/L) and a markedly elevated serum fluoride level (3.9 mg/L, normal range <

Effect of water fluoridation on the development of medial vascular calcification in uremic rats

April 6, 2014 | Toxicology | Martin-Pardillosa A, Sosaa C, Millanb A, Sorribasa V. | 318:40–50.
In summary, the effects of fluoride on renal function and vascular health are more complicated than expected. Our findings could help to decide whether the use of fluoride to improve the dental health of the population through indiscriminate practices, such as adding it to municipal drinking water, should be reconsidered and should be replaced by a fluoridation policy based on the health status of individuals.