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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Serum fluoride levels following commencement of methoxyflurane for patient analgesia in an ambulance service.

September 10, 2020 | BJA (British Journal of Anaesthesia) | Serah J. Allison, Paul D. Docherty, Dirk Pons, James G. Chase. | [Epub ahead of print]
Editor—Methoxyflurane, once a frequently used anaesthetic agent,1 is re-emerging as an inhalation analgesic. In modern practice, it is given in doses of up to 6 mL via a proprietary patient-controlled self-delivery device2  with an activated carbon filter designed to adsorb some methoxyflurane vapour from the patient's exhaled breath.3 Methoxyflurane is an organic vapour, identified as causing local environmental contamination when administered in anaesthesia or analgesia, and can subseque

Systematic review of water fluoridation.

September 12, 2000 | BMJ | McDonagh MS, Whiting PF, Wilson PM, Sutton AJ, Chestnutt I, Cooper J, Misso K, Bradley M, Treasure E, Kleijnen J. | 321:855.
Objective: To review the safety and efficacy of fluoridation of drinking water. Design: Search of 25 electronic databases and world wide web. Relevant journals hand searched; further information requested from authors. Inclusion criteria were a predefined hierarchy of evidence and objectives. Study validity was assessed with checklists. Two reviewers independently screened sources, extracted data, and assessed validity. Main outcome measures: Decayed, missing, and filled primary/permanent teet

Health Effects of Ingested Fluoride

1993 | National Research Council. The National Academies Press, Washington D.C. | Wagner BM, Burt BA, Cantor KP, Krewski D, Levy SM, McConnell EE, Whitford GM. |
Excerpts: INTRODUCTION Fluoridation of drinking water has been a subject of controversy for decades. Over the past 50 years, the incidence of dental caries (cavities) has declined considerably in the United States, an important health advance that most scientists attribute principally to increased access to fluoridated water and dental products. According to the U.S. Centers for Disease Control and Prevention, approximately 132 million Americans now receive drinking water that contains fluorid

Effects of acute fluoride exposure on the jejunum and ileum of rats: Insights from proteomic and enteric innervation analysis.

September 2020 | Science of The Total Environment | Aline Dionizio, Carina Guimaraes Souza Melo, Isabela Tomazini Sabino-Arias, Tamara Teodoro Araujo, Talita Mendes Oliveira Ventura, Aline Lima Leite, Sara Raquel Garcia Souza, Erika Xavier Santos, Alessandro Domingues Heubel, Juliana Gadelha Souza, Juliana Vanessa Colombo Martins Perles, Jacqueline Nelisis Zanoni, Marília Afonso Rabelo Buzalaf. | 741:140419/