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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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In situ efficacy of an experimental toothpaste on enamel rehardening and prevention of demineralisation: a randomised, controlled trial.

April 17, 2020 | BMC Oral Health | Creeth JE, Burnett GR, Souverain A, Gomez-Pereira P, Zero DT, Lippert F, Hara AT. | 20:118.
Background A novel sodium fluoride toothpaste containing lactate ion and polyvinylmethylether-maleic anhydride has been developed to promote enamel remineralisation and resistance to demineralisation. In this in situ study, we compared this toothpaste (‘Test’) with a stannous fluoride-zinc citrate (SnF2-Zn) toothpaste (‘Reference’) (both 1100–1150 ppm fluoride) and a fluoride-free toothpaste (‘Placebo’) using an enamel dental erosion-rehardening model. Methods In each phas

Co-exposure to non-toxic levels of cadmium and fluoride induces hepatotoxicity in rats via triggering mitochondrial oxidative damage, apoptosis, and NF-kB pathways.

April 17, 2020 | Environmental Science and Pollution Research | Arab-Nozari M, Mohammadi E, Shokrzadeh M, Ahangar N, Amiri FT, Shaki F. | [Epub ahead of print] doi: 10.1007/s11356-020-08791-4.
References Abarikwu SO, Njoku R-C, Lawrence CJ, Charles IA, Ikewuchi JC (2017) Rutin ameliorates oxidative stress and preserves hepatic and renal functions following exposure to cadmium and ethanol. Pharm Biol 55:2161–2169 CAS Article Google Scholar Abu-El-Zahab HS, Hamza RZ, Montaser MM, El-Mahdi MM, Al-Harthi WA (2019) Antioxidant, antiapoptotic, antigenotoxic, and hepatic ameliorative effects of L-carnitine and selenium on cadmium-induced hepatotoxicity

Assessment of phytotoxicity of leachates from landfilled waste and dust from foundry.

April 14, 2020 | Ecotoxicology | By Marta Bozym | https://doi.org/10.1007/s10646-020-02197-1
In contrast to chlorides and sulfates, fluorides are toxic to biota even at low concentrations (Stevens et al. 2000; Palmieri et al. 2014). Fluoride concentration was analyzed in the leachate, as it may be present in foundry waste. Organic binders are the main source of fluorides in foundry waste leachate (http://life-foundrysand.com). The fluoride concentration was low in all tested leachate. Plant resistance to fluoride depends on the plant species. Stevens et al. (1998) report the toxic for p