The metabolism of the central nervous system in experimental poliomyelitis.
December 1, 1942
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Journal of Experimental Medicine
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Racker E, Kabat H.
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76(6):579-85.
Excerpts
In an attempt to find the reason why the anaerobic breakdown of glucose in brain is less in poliomyelitis, experiments were performed using sodium fluoride as an inhibitor (Table II). The percentage inhibition resulting from fluoride was consistently higher in the normal than in the infected brain, particularly with lower concentrations of fluoride. The residual glycolysis in poliomyelitic brain treated with fluoride was equal to the glycolysis in normal brain with fluoride in every ex