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Recurrent benign aphthous stomatitis and fluoride allergy

Many years ago I consulted 2 patients suffering from recurrent aphthous ulceration to establish whether they had a toothpaste allergy. I thus proceeded to do many p-tests on the skin but without any positive results. However, replacement of the toothpaste with a simple soap quickly cured the ulcerations. A third case was referred to me with the same symptoms but in this case an unfortunate re-exposure caused a relapse of the ulcerations. At that time, it was unthinkable to speak of any kind of a