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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Survival analysis of caries incidence in African-American school-aged children.

September 20, 2018 | Journal of Public Health Dentistry | Ghazal TS, Levy SM, Childers NK, Carter KD, Caplan DJ, Warren JJ, Kolker JL. | 79(1):10-17.
Objectives To conduct an assessment of time-dependent covariates related to dental caries of the permanent dentition among a low socioeconomic status, understudied cohort of children, incorporating time-dependent covariates through the application of extended Cox proportional hazards modeling. Methods This study modeled the time to first cavitated dental caries in permanent teeth among school-aged children and assessed factors associated with this event. A cohort of 98 low socioeconom

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.

September 17, 2018 | Archives of Toxicology | Zhao Y, Li Y, Wang J, Manthari RK, Wang J. | [Epub ahead of print]
Excerpts: Apoptosis, characterized by nuclear fragmentation, chromatic condensation, and caspase activation, is a major molecular mechanism to eliminate cells (Oropesa-.vila et al. 2017 ). Apoptosis is observed widely in liver diseases (Cui et al. 2018 ; Potz et al. 2016 ). Fluoride, as an exogenous toxicant, has been reported to cause apoptosis in the liver (Khan et al. 2018 ). Song et al. (2015 ) reported that chronic fluoride exposure induced the liver apoptosis through activating the apopto