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Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children.

December 9, 2019 | BDJ Open | Amaechi BT, AbdulAzees PA, Alshareif DO, Shehata MA, de Carvalho Sampaio Lima PP, Abdollahi A, Kalkhorani PS, Evans V. | 5:18. doi:10.1038/s41405-019-0026-8
Abstract Objective This in situ study compared the effectiveness of two toothpastes containing hydroxyapatite or 500 ppm fluoride in promoting remineralization and inhibiting caries development. Materials and methods Two enamel blocks (human primary teeth), one sound and one with artificially-produced caries lesion, were exposed to toothpaste containing either 10% hydroxyapatite or 500 ppm F- (amine fluoride) via intra-oral appliance worn by 30 adults in two-arm double blind randomized