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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1a in primary cultured rat chondrocytes

February 2014 | International Journal of Molecular Medicine | Meng H, Zhang T, Liu W, Wang H, Wang C, Zhao Z, Liu N, Wang W. | 33(2):351-8.
Results of previous studies have shown that fluoride has a higher and special affinity for calcium in bone tissue, which could result in osteofluorosis (19,20). It has been reported that osteofluorosis may increase the severity of osteoarthritis (OA) characterized by progressive degeneration of articular cartilage (21,22). Chondrocyte apoptosis may be involved in the onset and development of osteoarthritic cartilage degeneration (23). Previously, chondrocytes were found to be responsible for the

Skeletal fluorosis in relation to drinking water, nutritional status and living habits in rural areas of Maharashtra, India

February 2014 | Journal of Environmental Science, Toxicology and Food Technology | Dhurvey V, Dhawas S. | 8(1):63-67
The present study was carried out during May 2010 to December 2011 in three villages which were randomly selected from Warora tehsil of Chandrapur district which is one of the endemic district of Maharashtra. . . . All the presently available ground water samples were collected and the mean fluoride concentration  was estimated by the ion analyser method, varied from 0.73 to 2.80 mg/L compared to the recommended  maximum permissible limit of 1.5 mg/L. As seen in Table 5 a high prevalence o