We appreciate your patience as we fix inconsistencies in the study tracker and research databases.

Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
  • Health Category:
  • Health Sub-Category:

  • Study Type:

  • Publish Date:

    -

Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking water: alterations in neuronal and cerebrovascular integrity

February 16, 1998 | Brain Research | Varner JA, Jensen KF, Horvath W, Isaacson RL. | 784(1-2):284-98.
“While the small amount of AlF in the drinking water of rats required for neurotoxic effects is surprising, perhaps even more surprising are the neurotoxic results of NaF at the dose given in the present study [1.0 ppm F]... The results of the present study indicate that more intensive neuropathological evaluations of F effects on brain may prove to be of value... In summary, chronic administration of AlF and NaF in the drinking water of rats resulted in distinct morphological alterations in t