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Contact dermatitis and stomatitis due to amine fluoride

Case Report For prevention of dental caries, a 17-year-old boy had intermittently used a gel containing different fluoride compounds over a period of 2 years. In the last 2 months, 1 to 2 days after application, he had developed itchy perioral erythematous papules and plaques, with vesicles of the oral mucosa. The lesions healed within 1 to 2 weeks, followed by perioral scaling. Other dentifrices were tolerated well. Patch tests were carried out with the European standard series, drug and oint