We appreciate your patience as we fix inconsistencies in the study tracker and research databases.

Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
  • Health Category:
  • Health Sub-Category:

  • Study Type:

  • Publish Date:

    -

Changed expressions of N-methyl-D-aspartate receptors in the brains of rats and primary neurons exposed to high level of fluoride

January 2018 | Journal of Trace Elements in Medicine and Biology | Wei N, Dong YT, Deng J, Wang Y, Qi XL, Yu WF, Xiao Y, Zhou JJ, Guan ZZ. | 45:31-40.
4. Discussion ... the numbers of Nissl bodies in neurons in the hippocampus and cortex of brains from both adult rats and their pups with fluorosis were lowered. Such reduction in Nissl bodies, showing large granular bodies consisting of rough endoplasmic reticulum with rosettes of free ribosomes carrying out protein synthesis, indicates injury of neurons [23].

Effect of fluoride on brain of albino-rabbit – An experimental study.

December 2017 | International Journal of Applied Research | Sahu SK, Pradham S, Sahu MC. | 3(3):818-821.
From Table 1: Gross and brain cyto-architecture changes of experimental animals at the end of 16 weeks. Changes in Brain Cytoarchitecture: The neurones lost their angular or pyramidal shape and acquired a plump, ovoid, rounded, or characteristic "ballooned" appearance (Figure 1). The nucleus was displaced to the periphery or axonal base and was shrunken, pyknotic, or absent. Reduction in the number of Purkinje neurones and in some areas even complete loss of neurones. Pyramidal neurones exhib