Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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The environmental impact of community caries prevention – part 3: water fluoridation.

August 26, 2022 | British Dental Journal | Duane B, Lyne A, Parle R, Ashley P. | 233:303–307
Authors and Affiliations Dental Public Health, Dublin Dental Hospital, Trinity College Dublin, D02 F859, Ireland Brett Duane Paediatric Dentistry, Eastman Dental Institute, Rockefeller, 21 University Street, London, WC1E 6DE, UK Alexandra Lyne & Paul Ashley Environmental Health Service National Water Operational Unit, Health Service Executive, Community Services Centre, Western Road, Clonmel, County Tipperary, E91 HT96, Ireland References UK Governm

Role of oxidative stress-mediated cell death and signaling pathways in experimental fluorosis.

August 17, 2022 | Chemico-Biological Interactions | Babu S, Manoharan S, Ottappilakkil H, Perumal E. | [Epub ahead of print]
Introduction Fluorine is one of the most reactive elements with high electronegativity and the second-highest electron affinity. It has an oxidation number of -1 and exists as either inorganic fluorides or organofluorine compounds [1,2]. F- exposure in humans occurs majorly from consuming water contaminated by F- from various natural and anthropogenic sources such as volcanic eruptions, mining residues, industrial effluents, phosphorus fertilizers, and certain domestic activities [3,4]. F

Further development of mathematical description for combined toxicity: A case study of lead–fluoride combination.

February 2, 2015 | Toxicology Reports | Panov VG, Katsnelson BA, Varaksin AN, Privalova LI, Kireyeva EP, Sutunkova MP, Valamina IE, Beresneva OY. | 2:297-307.
Highlights Rats were exposed during 6 weeks to repeated i.p. injections of lead acetate, sodium fluoride or both in doses 0.05 LD50. The development of intoxication was estimated quantitatively with 54 functional, biochemical and morphometric indices. For mathematical description of effects a response surface regression model containing linear and cross terms was used. 10 types of combined action were found thus confirming the result of the similar study on Pb and Cd.