From Table 1: Gross and brain cyto-architecture changes of experimental animals at the end of 16 weeks.
Changes in Brain Cytoarchitecture: The neurones lost their angular or pyramidal shape and acquired a plump, ovoid, rounded, or characteristic "ballooned" appearance (Figure 1). The nucleus was displaced to the periphery or axonal base and was shrunken, pyknotic, or absent. Reduction in the number of Purkinje neurones and in some areas even complete loss of neurones. Pyramidal neurones exhib
from Results and Discussion:
The neuronal damage and aggregation was observed in AlCl 3 + NaF treated group when compared to the control group where as less neuronal damage and aggregation was observed when Resveratrol administered along with AlCl 3 + NaF treatment. No morphological variation was observed in Resveratrol alone treated group as compared to the control group.
The amyloid protein plaques were formed in the AlCl 3 +NaF treated group as compared to the control group. The amyloid
from Results and discussion:
The present study evidenced that sodium fluoride consumption showed alteration in motor, cognitive, nociceptive behaviour and induced significant changes in the oxidative stress; membrane bound enzymes activities in rat. The administration of curcumin simultaneously with sodium fluoride reduced the oxidative stress, increased enzymes activities and improved behavioural abilities in rats. Vani and Reddy (2000) reported decreased somatic index of muscle and brain in
