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Dental fluorosis, nutritional status, kidney damage, and thyroid function along with bone metabolic indicators in school-going children living in fluoride- affected hilly areas of Doda District, Jammu and Kashmir, India.

References Das, K., & Mondal, N. K. (2016). Dental fluorosis and urinary fluoride concentration as a reflection of fluoride exposure and its impact on IQ level and BMI of children of Laxmisagar, Simlapal Block of Bankura District, W.B., India. Environmental Monitoring and Assessment, 188(4), 218.CrossRefGoogle Scholar Dean, H.T. (1942). The investigation of physiological effects by the epidemiological method. In F. R. Moulton (Ed.), “Fluorine and dental health,” (pp.23–31

The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission

In conclusion, the effects of NaF on a cell’s survival and integrity suggested that different concentrations NaF had direct toxic effects on the Neuro-2A cell line. NaF not only reduced the expression of select axonal proteins, but also prevented the secretion and delivery of the neurotransmitter glutamate.We found that expression of glutamate and its receptor, NMDAR, decreased with increasing dosages of NaF. Presumably, NaF can influence the generation and functions of axons, and limit