We appreciate your patience as we fix inconsistencies in the study tracker and research databases.

Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
  • Health Category:
  • Health Sub-Category:

  • Study Type:

  • Publish Date:

    -

Fluoride Induces Neuroinflammation and Alters Wnt Signaling Pathway in BV2 Microglial Cells.

August 2017 | Inflammation | Chen R, Zhao LD, Liu H, Li HH, Ren C, Zhang P, Guo KT, Zhang HX, Geng DQ, Zhang CY. | 40(4):1123-1130.
Fluoride exposure increases IL-1B and TNF-a production and changes the cellular oxidation and antioxidation status [5, 19]. Neuroinflammation seems to be an important mediator of the effects of fluoride. Neuroinflammation, which is mediated by microglia, contributes to most pathological neurologic processes, including CNS infections, ischemic stroke, neurodegenerative disease, and anesthetic neurotoxicity. Increased pro-inflammatory mediator production is thought to cause neuronal cell d

Alteration of paraoxonase, arylesterase and lactonase activities in people around fluoride endemic area of Tamil Nadu, India.

August 2017 | Clinica Chimica Acta | Arulkumar M, Vijayan R, Penislusshiyan S, Sathishkumar P, Angayarkanni J, Palvannan T. | Aug;471:206-215.
Excerpts .. High fluoride content in ground and surface water is a serious ecological problem for many countries including Algeria, Argentina, Australia, Canada, China, India, Iran, Iraq, Japan, Kenya, New Zealand, Libya, Turkey, South Africa, Srilanka, Thailand and the United States [1]. … In this study, 3 districts of Tamil Nadu namely (i) Salem, (ii) Dharmapuri and (iii) Krishnagiri were selected based on the prevalence of high fluoride contaminated water in order to assess its toxici