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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Effectiveness of resin based sealants with and without fluoride placed in a high caries risk population : multicentric 2 year randomised clinical trial.

June 2018 | Caries Research | Muller-Bolla M, Courson F, Lupi-Pegurier L, Tardieu C, Mohit S, Staccini P, Velly AM. | 52:312–322.
Comments on this article in the British Dental Journal, 2019, Jan 11; 226(1)39. The presence of fluoride in the sealant material is less important. ... It was found that sealant placement was effective at preventing carious lesions and that this protective effect was present regardless of the absence of fluoride in the sealant material. Other risk factors considered included deep fissures in permanent molars, the presence of non-cavitated lesions and previous caries experience in the deci