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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Exposure to Fluoride induces apoptosis in liver of ducks by regulating Cyt-C/Caspase 3/9 signaling pathway.

August 16, 2021 | Ecotoxicology and Environmental Safety | Ouyang Z, Yang B, Yi J, Zhu S, Lu S, Liu Y, Li Y, Li Y, Mehmood K, Hussain R, Ijaz M, Guo J, Tang Z, Li Y, Zhang H. | 224:112662.
Highlights Long-term exposure NaF induced hepatotoxicity in ducks. NaF exposure caused liver granule and vacuolar degeneration observed by histological analysis. The mechanism of NaF exposure on hepatotoxicity involving activating autophagy and apoptosis. Cyt-C/Caspase 3/9 signaling pathway activation target cell death. Abstract Fluorine being a well-known and essential element for normal physiological functions of tissues of different organisms is frequ

Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway.

August 3, 2021 | Oxidative Medicine and Cellular Longevity | Song Y, Zhang Y, Zhang P, Yu P, Shang X, Lu Y, Li Y, Gao H. | Article ID 6693921
1. Introduction Fluoride is one of the essential microelements in the body. Long-term excessive intake of fluoride will cause systemic physiological and pathological changes [1]. Fluoride can not only damage bone organs but also accumulate in brain tissue through the blood-brain barrier, affecting the shape and function of brain nerve cells [2, 3]. In recent years, fluoride pollution is serious due to the development of industry. Meanwhile, increased fluorine in water will cause a certain toxic