The onset of chronic fluorosis is insidious and may be confused with chronic debilitating diseases such as osteoarthritis . . .
* https://pubmed.ncbi.nlm.nih.gov/5463662/
It is quite possible that endemic centres [of skeletal fluorosis] exist but that the cause of the disabling spondylitis or other joint affections has not been determined, and a diagnosis of chronic arthritis has resulted. Few cases in Canada or the United States will be found to be as dramatic as that recorded here from Southwest China, but by calling attention to the advanced stage of this condition help may be afforded to the diagnosis of early cases.
... During our anthropological studies
Crippling fluorosis... is characterized by dense bones, exostoses, neurologic complications due to bony overgrowth, osteoarthritis, and ligamentous calcification.
... new bone formed under the stimulus of fluoride administration may exhibit various degrees of osteosclerosis, osteoporosis, osteomalacia, and architectural disorganization. Of these manifestations, only osteosclerosis increases bone strength. When fluoride is used therapeutically, therefore, it is obvious that conditions must be
EDITORIAL:
In 1854 Maument (1) administered to a dog from 20 to 120 mg sodium fluoride daily for four months. He observed an enlargement of the neck which he interpreted as a goiter. Ever since then conflicting data concerning the action of fluoride on the thyroid gland have appeared in the medical literature. In the early part of this century several authors concurred that fluoride intake may contribute to the production of goiter. This concept led to the administration of sodium fluoride fo
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... The supporting cancer hazard evidence was an animal study sponsored by the government’s National Toxicology Program (Lancet, Feb 3, p 282). Since then, the Public Health Service has responded to this and similar news stories by reaffirming its confidence in the safety and effectiveness of fluoridated drinking water. Th
... The present investigation concerns the influence of inorganic fluorine compounds on chromosomes in bone marrow and on the mytotic activity of epithelial cells of the cornea in female white rats. The animals were exposed 6 hours a day, six days a week, for 5 months, to the inhalation of cryolite (Na3AlF6) in concentrations of 3, 1, and 0.5 mg/m3 (calculated as fluoride ion), which is frequently encountered in the air of electrolysis areas of aluminum plants, and also of a mixture of 0.5 mg/m3
