Red blood cell glucose metabolism in human chronic fluoride toxicity
1991
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Bulletin of Environmental Contamination and Toxicology
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Saralakumari D, Rao PR.
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47:834-39.
Fluoride is a well known inhibitor of many enzyme systems in vitro (Shahed etal. 1979; Messer 1984). The most widely studied classic example of fluoride inhibition is its potent inhibition of glycolysis, specifically its action on the enzyme enolase (Warburg and Christian 1941; Shearer and Suttie 1970; Repaske and Suttie 1979; Shahed et al. 1979). Despite the plethora of in vitro studies on the effects of fluoride on the enzyme activity, there is a paucity of information concerning the in vivo m