Chronic treatment with fluoride affects the jejunum: insights from proteomics and enteric innervation analysis.
February 16, 2018
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Scientific Reports
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Dionizio AS, Melo CGS, Sabino-Arias IT, Ventura TMS, Leite AL, Souza SRG, Santos EX, Heubel AD, Souza JG, Perles JVCM, Zanoni JN, Buzalaf MAR.
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8(1):3180.
EXCERPTS
... Generally, many studies report Rab proteins as molecules present in the CNS and their specific roles. Although marked differences distinguish the neuronal function between the ENS [Enteric Nervous System] and CNS, their similarities allow the use of some principles established for the brain environment to be reapplied in the enteric context 38. Several cellular processes can be altered and promote the enteric neuronal alterations caused by F effects through mechanisms involving the