Neurotoxicity induced by fluoride in rat cerebral cortex
October 2016
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International Journal of Current Microbiology and Applied Sciences
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Shashi A and Kumar J.
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5(10):938-951.
In cerebral cortex of the rats, treated with 100 ppm of sodium fluoride, there was disorganization of granular cell layer. The granule cells were accumulated in the form of clumps. Some pyramidal neurons showed chromatolysis (Fig. 2) and were shrunken with vacuolation around them (Fig. 4). The nuclei of some pyramidal neurons were eccentric in neuroplasm and others were showing necrosis. Some granule cells were swollen in shape and size (Fig. 5).
... In rats treated with 200 ppm of sodium flu