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Does fluoride ingestion affect developing immune system cells?

Introduction Generally about half of the fluoride absorbed is deposited in bone. It was found in Finland (1) that the fluoridation of a water supply greatly increased the rate of fluoride accumulation in bone, from a mean of 11 ppm annually in low-fluoride areas to a mean of 44 ppm in the fluoridated people. In a warmer climate with a very 'soft' water supply the rate of increase may be more rapid. In a pilot study in Melbourne (2) the annual fluoride concentration increase in alveolar bone in