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Chronic toxicity of dietary sodium monofluorophosphate in growing rats, with special reference to kidney changes.

MATERIAL AND METHODS: Male white rats weighing about 100 grams at the start of the experiments were used in the study. They were raised in a standardized way by the Anticimex Co., Stockholm on pellets containing about 28 ppm fluoride and tap water containing about 0.1 ppm fluoride. In a four-week pilot study 20 rats were divided in 5 groups of four animals each for the preliminary testing of two concentrations of Na2PO3F in comparison with two concentrations of NaF and one control group. Ever