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Sodium fluoride affects zebrafish behaviour and alters mRNA expressions of biomarker genes in the brain: Role of Nrf2/Keap1

Sodium fluoride (NaF), used as pesticides and for industrial purposes are deposited in the water bodies and therefore affects its biota. Zebrafish exposed to NaF in laboratory condition showed hyperactivity and frequent surfacing activity, somersaulting and vertical swimming pattern as compared to the control group. Reactive oxygen species level was elevated and glutathione level was depleted along with increased malondialdehyde content in the brain. Levels of glutathione-s-transferase (GST), ca

Placental Transfer of Fluoride and Tin in Rats Given Various Fluoride and Tin Salts

Fetal fluoride and tin levels. Two-way analysis of variance of the values for animals fed salts containing fluoride indicated that the variable of test salt did not have a significant effect on fetal fluoride level (P > 0.25). However, the dietary level of fluoride had a highly significant effect (P << 0.01 ) on the fetal level of fluoride. The fetuses of rats fed the 200 ppm fluoride diets had significantly (P < 0.05) higher fluoride levels than the fetuses of rats fed diets with 0,