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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Fluoride metabolism: its significance in water fluoridation.

March 1956 | The Journal of the American Dental Association | Harold C. Hodge | 52(3):307-314.
Excerpt The purpose of this report is the review of the present knowledge of the metabolism of fluorides, particularly in the human body, and the use of this knowledge in estimating the factors of safety in water fluoridation. In this discussion, many of the biological effects of fluorides (purported or well-established) will receive no mention. On the other hand, there are a few important biological effects of fluorides so well studied that there is an established relation between the effect a

A Meta-Analysis of Stressors from the Total Environment Associated with Children’s General Cognitive Ability

July 29, 2020 | International Journal of Environmental Research and Public Health | Frances M. Nilsen, Jazmin D.C. Ruiz, and Nicolle S. Tulve. |
Excerpt: page 11 ... Fluoride was observed to have the greatest increase in impacting cognitive ability (OR = 1.40, p  0.05) and it is often reported to affect memory and cause cognitive deficits [241]. (our emphasis) Reference 241 Smith, P.W. Memory Maintenance and Cognitive Decline. In Anti-Aging Therapeutics Volume XVI; Klatz, R., Goldman, R., Eds.; A4M Publications: Chicago, IL, USA, 2015.

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

May 8, 2020 | Archives of Toxicology | Guth S, Huser S, Roth, A, Degen G, Diel P, Edlund K, Eisenbrand G, Engel KH, Epe B, Grune T, Heinz V, Henle T, Humpf HU, Jager H, Joost HG, Kulling SE, Lampen A, Mally A, Marchan R, Marko D, Muhle E, Nitsche MA, Rohrdanz E, Stadler R, van Thriel C, Vieths S, Vogel RD, Wascher E, Watzl C, Nothlings U, Hengstler JG. | 94:1375–1415