Study Tracker

Human exposure assessment of fluoride from tea (Camellia sinensis L.): A UK based issue?

May 2013 | Food Research International | Chan L, Mehra A, Sakat S, Lynch P. | 51(2):564-570

Highlights • Fluoride concentrations were determined in UK tea infusions and products. • UK economy tea contained elevated fluoride, comparable to Chinese brick tea. • Fluoride concentration significantly varies depending upon the type of tea. • We report a risk of high exposure to fluoride if consuming 1L/day of Economy tea. • Tea consumption alone can exceed the dietary reference intake of fluoride.

Fluoride exposure changed the structure and the expressions of reproductive related genes in the hypothalamus-pituitary-testicular axis of male mice

May 8, 2015 | Chemosphere | Han H, Sun Z, Luo G, Wang C, Wei R, Wang J. | 135:297-303.

Neurobehavioural effects of exposure to fluoride in the earliest stages of rat development

August 1, 2015 | Physiology & Behavior | Bartos M, Gumilar F, Bras C, Gallegos CE, Giannuzzi L, Cancela LM, Minetti A. | 147:205-12

Small molecule fluoride toxicity agonists

April 23, 2015 | Chemistry & Biology | Nelson JW, Plummer MS, Blount KF, Ames TD, Breaker RR. | 22(4):527-34.

INTRODUCTION Although fluoride is commonly added to oral hygiene products to increase the strength of tooth enamel, it also has substantial anti-bacterial effects (Barbier et al., 2010; Li, 2003). For example, when in complex with a divalent metal ion and ADP, fluoride forms a nonfunctional mimic of ATP that can inhibit enolase (Curran et al., 1994; Qin et al., 2006), and similar complexes can inhibit a large diversity of other metabolic enzymes including phosphatases (Barbier et al., 2010; N

Fluoride in drinking water and diet: the causative factor of chronic kidney diseases in the North Central Province of Sri Lanka

July 2015 | Environmental Health and Preventive Medicine | Dharmaratne RW. | 20(4):237-42.

Protective effects of blackberry and quercetin on sodium fluoride-induced oxidative stress and histological changes in the hepatic, renal, testis and brain tissue of male rat

May 1, 2015 | Journal of Basic and Clinical Physiology and Pharmacology | Hamza RZ, El-Shenawy NS, Ismail HA. | 26(3):237-51.

Exocyclic DNA adducts in sheep with skeletal fluorosis resident in the proximity to the Portoscuso-Portovesme industrial estate on Sardinia Island, Italy

April 9, 2015 | Toxicology Research | Peluso ME, Munnia A, Giese RW, Catelan D, Rocca S, Farigu S, Leoni A, Bruzzone M, Ceppi M, BiggeriA. | 4:986-993

   

Sodium fluoride induces apoptosis through reactive oxygen species-mediated endoplasmic reticulum stress pathway in Sertoli cells

April 1, 2015 | Journal of Environmental Sciences (China). | Yang Y, Lin X, Huang H, Feng D, Ba Y, Cheng X, Cui L. | 30:81-9.

Fluorine toxicosis and industry.

March-April 1970 | American Industrial Hygiene Association Journal | Shupe JL. | 31: 240-247.

The onset of chronic fluorosis is insidious and may be confused with chronic debilitating diseases such as osteoarthritis . . . * https://pubmed.ncbi.nlm.nih.gov/5463662/

Fluorosis with report of an advanced case.

February 1950 | Canadian Medical Association Journal | Kilborn LG, Outerbridge TS, Lei HP. | 62:135-141.

It is quite possible that endemic centres [of skeletal fluorosis] exist but that the cause of the disabling spondylitis or other joint affections has not been determined, and a diagnosis of chronic arthritis has resulted. Few cases in Canada or the United States will be found to be as dramatic as that recorded here from Southwest China, but by calling attention to the advanced stage of this condition help may be afforded to the diagnosis of early cases. ... During our anthropological studies