Studies of relationships between the polymorphism of COMT gene and plasma proteomic profiling and children’s intelligence in high fluoride areas
May 2012
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Master’s Dissertation, Huazhong University of Science & Technology,
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Zhang X.
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Fluoride (F) widely exists in environment with a significant increase in body burden accumulation in recent years. Internal exposure to F due to diet including food, water, fluoride-containing dental products like toothpaste and fluoride supplements, is extensively researched. Additionally, industrial pollution and coal burning have also been reported to be major sources of internal F exposure, especially in China.
It is known that excessive fluoride intake over a long period of time may resu