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Exposure to excessive fluoride during hemodialysis

Discussion These data indicate that a patient maintained by hemodialysis in a community using fluoridated water may be exposed to a fluoride concentration higher than that present in tap water if the deionizer is allowed to become exhausted while the patient is being dialyzed. The concentration reached 520 uM in the laboratory deionizer and 230 M in the patient's model. Since the concentration of fluoride in blood returning from the dialyzer is about one-half to two-thirds that in the dialysate