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Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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Induction of apoptosis by sodium fluorosilicate treatment in human osteogenic sarcoma (HOS) cells.

January-February 2005 | Anticancer Research | Song JS, Park YD, Hyun JW, Kim JH. | 25(1A):391-5.
Materials and Methods Fluorine compounds and cell culture. The fluorine compounds used in this study were sodium fluorosilicate (F6Na2Si, Fluka, Switzerland) and sodium fluoride (NaF, Sigma, USA)... Results Cytotoxicity of sodium fluorosilicate. To determine a concentration which leads to 50% growth inhibition (IC50 values), we performed cytotoxicity analysis by MTT assay. HOS, MG-63, KB and A-253 cells were treated with 0-250 ppm of sodium fluorosilicate or sodium fluoride. The cells were