Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
September 7, 2022
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Chemosphere
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Zhao Q, Pan W, Li J, Yu S, Liu Y, Zhang X, Qu R, Zhang Q, Li B, Yan X, Ren X, Qiu Y
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Epub ahead of print
Highlights
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Arsenic and/or fluoride exposure can impair spatial learning and memory ability in offspring rats, and low-dose combined exposure produces stronger neurotoxicity than exposure alone.
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Arsenic and/or fluoride exposure can disrupt synaptic structure and function, which in turn leads to neurotoxicity.
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Arsenic and fluoride exposure have an interactive effect on the expression of autolysosome-related proteins in rat hippocampal neurons, as shown