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Enhancement of inflammation by fluorides

Application of ammonium fluoride under an occlusive patch to the abdomen of a rabbit converts a simple scratch into a double row of sterile pustules. Sodium fluoride produces a similar response, but ammonium chloride does not produce pustules. . . . It appears that tissue damage and the presence of fluorides result in the ‘sterile pustular response.’ This can be called ‘enhancement of inflammation.’ The concentration of fluoride used will not induce inflammation, but it will enhance inf