-

Lithium in Drinking Water as a Public Policy for Suicide Prevention: Relevance and Considerations.

Although suicide is considered a major preventable cause of mortality worldwide, we do not have effective strategies to prevent it. Lithium has been consistently associated with lowering risk of suicide. This effect could occur at very low concentrations, such as trace doses of lithium in tap water. Several ecological studies and recent meta-analysis have suggested an inverse association between lithium in water and suicide in the general population, with a lack of knowledge of clinically si

The association between fluoride in water and blood pressure in children and adolescents.

References Flynn, J. T. et al. Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics 140, e20171904 (2017). PubMed  Google Scholar Ostchega, Y. et al. Trends of elevated blood pressure among children and adolescents: data from the National Health and Nutrition Examination Survey1988-2006. Am. J. Hypertens. 22, 59–67 (2009). PubMed  Google Scholar Leng, B., Jin, Y., Li, G., Chen, L. & Jin, N

Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.

1. Introduction Neurodevelopmental disorders such as impairment of learning and memory, and cognitive dysfunction, are of serious concern due to the health risks and consequences on the developing brain resulting from exposure to exogenous chemicals [1], [2], [3]. The assessment of developmental neurotoxicity (DNT) is not a mandatory requirement in the European Union or the United States of America and is not routinely conducted. However, it may be undertaken when data from developmental and/

Potential fluoride exposure from selected food crops grown in high fluoride soils in the Makueni County, south-eastern Kenya.

Makueni County, located in south-eastern Kenya, faces challenges such as limited potable water and restricted food supplies as the result of semi-aridity. High fluoride (F) concentrations have been reported in drinking water with resultant dental fluorosis affecting the local population. To determine the potential F exposure through the consumption of food crops grown in the area, F concentration was assessed in the main five locally grown and consumed crops. Additionally, the water-solu

The Effects of Vitamin D Application on NaF-Induced Cytotoxicity in Osteoblast Cells (hFOB 1.19).

Agalakova NI, Gusev GP (2012) Molecular mechanisms of cytotoxicity and apoptosis induced by inorganic fluoride. ISRN Cell Biol 403835. https://doi.org/10.5402/2012/403835 Perumal E, Paul V, Govindarajan V, Panneerselvam L (2013) A brief review on experimental fluorosis. Toxicol Letter 233:236–251. https://doi.org/10.1016/j.toxlet.2013.09.005 - DOI Song GH, Gao JP, Chun FW et al (2014) Sodium fluoride induces apoptosis in the kidney of rats through ca

Salivary fluoride concentration following toothbrushing with and without rinsing: a randomised controlled trial.

References Marinho VC, Higgins JP, Sheiham A, Logan S. Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. 2003;(1):CD002278. Marinho VCC. Cochrane reviews of randomized trials of fluoride therapies for preventing dental caries. Eur Arch Paediatr Dent. 2009;10(3):183–91. Article  Google Scholar Levine RS. What concentration of fluoride toothpaste should dental teams be recommending? Evid Based Dent. 2019;20(